AUTOIMMUNE PROGESTERONE DERMATITIS MANIFESTING AS GENERALIZED FIXED DRUG ERUPTION

Autoimmune progesterone dermatitis manifesting as generalized fixed drug eruption

Autoimmune progesterone dermatitis manifesting as generalized fixed drug eruption

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Abstract: Autoimmune progesterone dermatitis is an uncommon, poorly recognized and under-diagnosed catamenial dermatosis associated with hypersensitivity reactions to progestagens.Most cases manifest as urticaria, eczema or erythema Collections multiforme-like.A 26-year-old woman developed violaceous plaques on the groin and abdomen, 4 days after a spontaneous abortion resolved with uterine curettage.

The lesions recurred once Course a pied - Accessoires - Nutrition - Jujubes monthly at the same sites, mimicking a fixed drug eruption.Although the histopathology was compatible with fixed drug eruption, positive intradermal testing and symptomatic improvement after using oral contraceptive pills gave us a clue to the diagnosis.

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